McMillen, Edmund. The Binding Of Isaac.

This video game is a dungeon crawler in which you play as a boy name Isaac, attempting to escape from his mother who wishes to sacrifice him and prove her religious devotion.

Annotation
McMillen, Edmund and Florian Himsl. The Binding of Isaac. Valve Corporation, 2011. PC.

Quotes and Notes
The religious mother in The Binding of Isaac who hears the voice of God telling her to first take away everything from her son and then to sacrifice him Psychosis and religious delusion tied to filicide or infanticide "Reminds me of the Andrea Yates case in this respect but Isaac’s mother attempts to stab Isaac to death, versus drowning him."

"The use of the knife ties to the Biblical story BUT it is Isaac’s father, Abraham, who is told by God to sacrifice his son; he binds Isaac to an altar and, at the last minute, an angel shows up and stops Abraham"

"Why change the gender of the God fearing parent in this video game?" Mother normal at first, but as the final boss, we only see large, swollen body parts, never the entire body of the mother